Ingredients index

Milk Fat Globule Membrane

Our Vivinal® Milk Fat Globule Membrane (MFGM) is a whey protein concentrate that’s rich in MFGM components, which are obtained during the mild processing of pasteurized cheese whey. Vivinal® MFGM contains bioactive proteins and lipids like IgG and lactoferrin, phospholipids and gangliosides. MFGM can be added to infant milk formula to potentially support infant cognitive development

Li, F., Wu, S. S., Berseth, C. L., Harris, C. L., Richards, J. D., Wampler, J. L., Zhuang, W., Cleghorn, G., Rudolph, C. D., Liu, B., Shaddy, D. J., & Colombo, J. (2019). Improved Neurodevelopmental Outcomes Associated with Bovine Milk Fat Globule Membrane and Lactoferrin in Infant Formula: A Randomized, Controlled Trial. Journal of Pediatrics. https://doi.org/10.1016/j.jpeds.2019.08.030





Timby, N., Domellöf, E., Hernell, O., Lönnerdal, B., & Domellöf, M. (2014). Neurodevelopment, nutrition, and growth until 12 mo of age in infants fed a low-energy, low-proteinformula supplemented with bovine milk fat globule membranes: A randomized controlled trial. American Journal of Clinical Nutrition. https://doi.org/10.3945/ajcn.113.064295





Timby, N., Domellöf, M., Lönnerdal, B., & Hernell, O. (2017). Supplementation of infant formula with bovine milk fat globule membranes. In Advances in Nutrition. https://doi.org/10.3945/an.116.014142.





Li, X., Peng, Y., Li, Z., Christensen, B., Heckmann, A. B., Stenlund, H., Lönnerdal, B., & Hernell, O. (2019). Feeding Infants Formula With Probiotics or Milk Fat Globule Membrane: A Double-Blind, Randomized Controlled Trial. Frontiers in Pediatrics. https://doi.org/10.3389/fped.2019.00347





Timby, N., Domellöf, M., Lönnerdal, B., & Hernell, O. (2017). Supplementation of infant formula with bovine milk fat globule membranes. In Advances in Nutrition. https://doi.org/10.3945/an.116.014142.



.

Protein content (%)
Phospholipid content (%)
IgG content (%)
Lactoferrin content (mg/100g)
72
7.4
4
375
  • What is MFGM? 

    MFGM stands for Milk Fat Globule Membrane, a complex layer that surrounds milk fat globules secreted from milk-producing cells in human and animals. Vivinal® MFGM is an infant formula-grade whey protein concentrate that contains bioactive proteins and lipids like IgG and lactoferrin, phospholipids and gangliosides.

  • What are the health benefits of MFGM?

    MFGM plays a potential role in infant cognitive development

    Timby, N., Domellöf, M., Lönnerdal, B., & Hernell, O. (2017). Supplementation of infant formula with bovine milk fat globule membranes. In Advances in Nutrition. https://doi.org/10.3945/an.116.014142.



    . Clinical studies have shown that consumption of a formula supplemented with MFGM improved cognitive performance in infants

    Li, F., Wu, S. S., Berseth, C. L., Harris, C. L., Richards, J. D., Wampler, J. L., Zhuang, W., Cleghorn, G., Rudolph, C. D., Liu, B., Shaddy, D. J., & Colombo, J. (2019). Improved Neurodevelopmental Outcomes Associated with Bovine Milk Fat Globule Membrane and Lactoferrin in Infant Formula: A Randomized, Controlled Trial. Journal of Pediatrics. https://doi.org/10.1016/j.jpeds.2019.08.030
    Timby, N., Domellöf, E., Hernell, O., Lönnerdal, B., & Domellöf, M. (2014). Neurodevelopment, nutrition, and growth until 12 mo of age in infants fed a low-energy, low-proteinformula supplemented with bovine milk fat globule membranes: A randomized controlled trial. American Journal of Clinical Nutrition. https://doi.org/10.3945/ajcn.113.064295



    . Clinical studies have also found that infant formula supplemented with MFGM may have beneficial effects on infant immune function

    Li, X., Peng, Y., Li, Z., Christensen, B., Heckmann, A. B., Stenlund, H., Lönnerdal, B., & Hernell, O. (2019). Feeding Infants Formula With Probiotics or Milk Fat Globule Membrane: A Double-Blind, Randomized Controlled Trial. Frontiers in Pediatrics. https://doi.org/10.3389/fped.2019.00347
    Timby, N., Hernell, O., Vaarala, O., Melin, M., Lönnerdal, B., & Domellöf, M. (2015). Infections in infants fed formula supplemented with bovine milk fat globule membranes. Journal of Pediatric Gastroenterology and Nutrition. https://doi.org/10.1097/MPG.0000000000000624



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  • What are the processing benefits of Vivinal® MFGM

    Vivinal® MFGM enables greater flexibility in recipe formulation, thanks to the fact that it is a dry-blend infant formula-grade ingredient.

  • Product substantiation and benefits Vivinal® MFGM
    • Dry blend powder
    • Preserves bioactives due to mild processing
    • Supports brain and cognitive development

      Li, F., Wu, S. S., Berseth, C. L., Harris, C. L., Richards, J. D., Wampler, J. L., Zhuang, W., Cleghorn, G., Rudolph, C. D., Liu, B., Shaddy, D. J., & Colombo, J. (2019). Improved Neurodevelopmental Outcomes Associated with Bovine Milk Fat Globule Membrane and Lactoferrin in Infant Formula: A Randomized, Controlled Trial. Journal of Pediatrics. https://doi.org/10.1016/j.jpeds.2019.08.030
      Timby, N., Domellöf, E., Hernell, O., Lönnerdal, B., & Domellöf, M. (2014). Neurodevelopment, nutrition, and growth until 12 mo of age in infants fed a low-energy, low-proteinformula supplemented with bovine milk fat globule membranes: A randomized controlled trial. American Journal of Clinical Nutrition. https://doi.org/10.3945/ajcn.113.064295


    • Supports immune health 

      Li, X., Peng, Y., Li, Z., Christensen, B., Heckmann, A. B., Stenlund, H., Lönnerdal, B., & Hernell, O. (2019). Feeding Infants Formula With Probiotics or Milk Fat Globule Membrane: A Double-Blind, Randomized Controlled Trial. Frontiers in Pediatrics. https://doi.org/10.3389/fped.2019.00347
      Timby, N., Hernell, O., Vaarala, O., Melin, M., Lönnerdal, B., & Domellöf, M. (2015). Infections in infants fed formula supplemented with bovine milk fat globule membranes. Journal of Pediatric Gastroenterology and Nutrition. https://doi.org/10.1097/MPG.0000000000000624


  • Why choose MFGM from FrieslandCampina Ingredients?

    Vivinal® MFGM offers preservation of the bioactive components that are part of MFGM in a whey protein concentrate. Vivinal® MFGM is ideal for use in dry-blend application, where the final formula can also benefit from keeping these bioactive components intact.

Want to know more about the benefits of MFGM?

FrieslandCampina Ingredients provides high quality MFGM to apply in your products for babies and young children. Our innovations are backed by over 75 years’ experience in manufacturing and research in the field of early life nutrition. Get in touch for personalised advice on how to bring the benefits of MFGM to your infant milk and young child formula solution.

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