Milk Fat Globule Membrane

MFGM stands for Milk Fat Globule Membrane, a complex layer that surrounds milk fat globules secreted from milk-producing cells in human and animals. Vivinal® MFGM is an infant formula-grade whey protein concentrate that contains bioactive proteins and lipids like IgG and lactoferrin, phospholipids and gangliosides.

MFGM plays a potential role in infant cognitive development

Timby, N., Domellöf, M., Lönnerdal, B., & Hernell, O. (2017). Supplementation of infant formula with bovine milk fat globule membranes. In Advances in Nutrition. https://doi.org/10.3945/an.116.014142.



. Clinical studies have shown that consumption of a formula supplemented with MFGM improved cognitive performance in infants

Li, F., Wu, S. S., Berseth, C. L., Harris, C. L., Richards, J. D., Wampler, J. L., Zhuang, W., Cleghorn, G., Rudolph, C. D., Liu, B., Shaddy, D. J., & Colombo, J. (2019). Improved Neurodevelopmental Outcomes Associated with Bovine Milk Fat Globule Membrane and Lactoferrin in Infant Formula: A Randomized, Controlled Trial. Journal of Pediatrics. https://doi.org/10.1016/j.jpeds.2019.08.030
Timby, N., Domellöf, E., Hernell, O., Lönnerdal, B., & Domellöf, M. (2014). Neurodevelopment, nutrition, and growth until 12 mo of age in infants fed a low-energy, low-proteinformula supplemented with bovine milk fat globule membranes: A randomized controlled trial. American Journal of Clinical Nutrition. https://doi.org/10.3945/ajcn.113.064295



. Clinical studies have also found that infant formula supplemented with MFGM may have beneficial effects on infant immune function

Li, X., Peng, Y., Li, Z., Christensen, B., Heckmann, A. B., Stenlund, H., Lönnerdal, B., & Hernell, O. (2019). Feeding Infants Formula With Probiotics or Milk Fat Globule Membrane: A Double-Blind, Randomized Controlled Trial. Frontiers in Pediatrics. https://doi.org/10.3389/fped.2019.00347
Timby, N., Hernell, O., Vaarala, O., Melin, M., Lönnerdal, B., & Domellöf, M. (2015). Infections in infants fed formula supplemented with bovine milk fat globule membranes. Journal of Pediatric Gastroenterology and Nutrition. https://doi.org/10.1097/MPG.0000000000000624



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Vivinal® MFGM enables greater flexibility in recipe formulation, thanks to the fact that it is a dry-blend infant formula-grade ingredient.

• Dry blend powder
• Preserves bioactives due to mild processing
• Supports brain and cognitive development
  
  Li, F., Wu, S. S., Berseth, C. L., Harris, C. L., Richards, J. D., Wampler, J. L., Zhuang, W., Cleghorn, G., Rudolph, C. D., Liu, B., Shaddy, D. J., & Colombo, J. (2019). Improved Neurodevelopmental Outcomes Associated with Bovine Milk Fat Globule Membrane and Lactoferrin in Infant Formula: A Randomized, Controlled Trial. Journal of Pediatrics. https://doi.org/10.1016/j.jpeds.2019.08.030
  Timby, N., Domellöf, E., Hernell, O., Lönnerdal, B., & Domellöf, M. (2014). Neurodevelopment, nutrition, and growth until 12 mo of age in infants fed a low-energy, low-proteinformula supplemented with bovine milk fat globule membranes: A randomized controlled trial. American Journal of Clinical Nutrition. https://doi.org/10.3945/ajcn.113.064295
  
  
  
• Supports immune health 
  
  Li, X., Peng, Y., Li, Z., Christensen, B., Heckmann, A. B., Stenlund, H., Lönnerdal, B., & Hernell, O. (2019). Feeding Infants Formula With Probiotics or Milk Fat Globule Membrane: A Double-Blind, Randomized Controlled Trial. Frontiers in Pediatrics. https://doi.org/10.3389/fped.2019.00347
  Timby, N., Hernell, O., Vaarala, O., Melin, M., Lönnerdal, B., & Domellöf, M. (2015). Infections in infants fed formula supplemented with bovine milk fat globule membranes. Journal of Pediatric Gastroenterology and Nutrition. https://doi.org/10.1097/MPG.0000000000000624
  
  
  

Vivinal® MFGM offers preservation of the bioactive components that are part of MFGM in a whey protein concentrate. Vivinal® MFGM is ideal for use in dry-blend application, where the final formula can also benefit from keeping these bioactive components intact.