FrieslandCampina Ingredients

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Mother’s milk is complex by nature: so far, more than 200 oligosaccharide structures have been identified in human milk

German et al., 2008



, each of which is expected to have its own potential benefits for infant gut health and immunity. FrieslandCampina Ingredients’ latest GOS innovation, Vivinal® GOS-SL, is a complex solution that contains more than 100 oligosaccharide structures. Some of these structures are present in human milk such as galactosyllactoses 3’-GL, 4’-GL and 6’-GL and sialyllactoses 3’-SL and 6’-SL.

Elevating GOS for infant nutrition

Vivinal® GOS-SL has the same composition as Vivinal® GOS, including 3’-GL, 4’-GL and 6’-GL, but now also contains 3’-SL and 6’-SL from bovine milk origin. 3’-GL, 4’-GL, 6’-GL, 3’-SL and 6’-SL present in Vivinal® GOS-SL have the same structure as the ones in human milk.

*HMO and GOS structures adapted from literature

Thurl et al., 2017
Coulier et al., 2008
Van Leeuwen et al., 2014




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3’-GL, 4’-GL, 6’-GL, 3’-SL and 6’-SL present in Vivinal® GOS-SL have the same structure as the ones in human milk*.

*HMO and GOS structures adapted from literature

Thurl et al., 2017
Coulier et al., 2008
Van Leeuwen et al., 2014




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Immunity

3’-GL, 4’-GL and 6’-GL have been reported to have 6anti-infl ammatory eff ects5 and can promote the growth of beneficial gut bacteria6,7.

Brain health

3’-SL and 6’-SL have been associated with improved learning & memory, neurodevelopment, language development8,9 and reduced rotavirus, RSV and infl uenza virus infectivity10,11.

Gut health

GOS have been shown to stimulate the growth of Bifi dobacteria and Lactobacilli12,13, support normal gut transit14-17, stool consistency15 and mineral absorption18-21.

Produced through a unique process

Our unique production process ensures SL enrichment and guarantees consistent SL and GL levels in Vivinal® GOS-SL syrup.

  • Process begins by sourcing IFT grade whey permeate containing lactose and SLs.
  • FrieslandCampina Ingredients has developed a selective purifi cation and SL enrichment process to increase SLs on dm to min. 0.45%.
  • Purifi ed lactose stream enriched with SLs is used for enzymatic GOS production resulting in consistent GLs (3’-GL, 4’-GL, 6’-GL) to a level of min. 6.2% on dm.

Powering infant formula with SLs and GLs

Adding 6.5% Vivinal® GOS-SL syrup to an infant formula can provide 25% of the 3’-SL levels and 100% of the GL levels present in mature human milk22,23, while supporting key health benefits for infants – gut health, immunity, brain health – and possibly claim 5 HMOs (3’-GL, 4’-GL, 6’-GL, 3’-SL and 6’-SL) on pack and/or on point-of-sales materials*.

*Please note that the country-specific regulation defines what type of communication or claims are allowed per target group and application.

Gut health, immunity and brain health are top concerns of parents of 0-12  months old infants. Globally, 55% of parents fi nd gut health and cognitive development important, while immunity is the #1 concern24.

As the exclusive provider of GOS enriched with SL structures, we can help you diff erentiate your infant formula with oligosaccharides. We’re proud to play a global leadership role in the infant milk formula industry, backed by over 75 years of experience in early life nutrition.

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We have decades of expertise in delivering high quality ingredients that help people live their lives to the full. Want to know more about how we can collaborate with you to accelerate innovation and push the boundaries of nutrition? Speak to our experts today.

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