Discover Vivinal® GOS-SL
Mother’s milk is complex by nature: so far, more than 200 oligosaccharide structures have been identified in human milk
German et al., 2008
, each of which is expected to have its own potential benefits for infant gut health and immunity. FrieslandCampina Ingredients’ latest GOS innovation, Vivinal® GOS-SL, is a complex solution that contains more than 100 oligosaccharide structures. Some of these structures are present in human milk such as galactosyllactoses 3’-GL, 4’-GL and 6’-GL and sialyllactoses 3’-SL and 6’-SL.
Elevating GOS for infant nutrition
Vivinal® GOS-SL has the same composition as Vivinal® GOS, including 3’-GL, 4’-GL and 6’-GL, but now also contains 3’-SL and 6’-SL from bovine milk origin. 3’-GL, 4’-GL, 6’-GL, 3’-SL and 6’-SL present in Vivinal® GOS-SL have the same structure as the ones in human milk.
*HMO and GOS structures adapted from literature
Thurl et al., 2017
Coulier et al., 2008
Van Leeuwen et al., 2014

Supporting immunity
3’-GL, 4’-GL and 6’-GL have been reported to have anti-inflammatory effects
He et al., 2014
and can promote the growth of beneficial gut bacteria
Li et al., 2015
Meeusen et al., 2024
.
Supporting brain health
3’-SL and 6’-SL have been associated with improved learning & memory, neurodevelopment, language development
Oliveros et al., 2021
Oliveros et al., 2018
and reduced rotavirus, RSV and influenza virus infectivity
Laucirica et al., 2017
Duska-McEwen et al., 2014
.
Supporting gut health
GOS have been shown to stimulate the growth of Bifidobacteria and Lactobacilli
Ben et al., 2008
Fanaro et al., 2009
, support normal gut transit
Williams et al., 2014
Sierra et al., 2014
Costalos et al., 2008
Schmelze et al., 2003
, stool consistency
Sierra et al., 2014
and mineral absorption
Weaver et al., 2011
Whisner et al., 2013
Van den Heuvel et al., 2000
Paganini et al., 2017
Produced through a unique process
Our unique production process ensures SL enrichment and guarantees consistent SL and GL levels in Vivinal® GOS-SL syrup.
- Process begins by sourcing IFT grade whey permeate containing lactose and SLs.
- FrieslandCampina Ingredients has developed a selective purification and SL enrichment process to increase SLs on dm to min. 0.45%.
- Purified lactose stream enriched with SLs is used for enzymatic GOS production resulting in consistent GLs (3’-GL, 4’-GL, 6’-GL) to a level of min. 6.2% on dm.
Powering infant formula with SLs and GLs
Adding 6.5% Vivinal® GOS-SL syrup to an infant formula can provide 25% of the 3’-SL levels and 100% of the GL levels present in mature human milk
Austin et al., 2016
Sumiyoshi et al., 2004
, while supporting key health benefits for infants – gut health, immunity, brain health – and possibly claim 5 HMOs (3’-GL, 4’-GL, 6’-GL, 3’-SL and 6’-SL) on pack and/or on point-of-sales materials*.
*Please note that the country-specific regulation defines what type of communication or claims are allowed per target group and application.
Gut health, immunity and brain health are top concerns of parents of 0-12 months old infants. Globally, 55% of parents find gut health and cognitive development important, while immunity is the #1 concern
Global consumer study Early Life Nutrition Innova and RFC, 2020
.
Want to know more?
As the exclusive provider of GOS enriched with SL structures, we can help you differentiate your infant formula with oligosaccharides. We’re proud to play a global leadership role in the infant milk formula industry, backed by over 75 years of experience in early life nutrition.


Gut health, immunity and brain health are top concerns of parents of 0-12 months old infants. Globally, 55% of parents find gut health and cognitive development important, while immunity is the #1 concern 