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Discover Vivinal® GOS-SL


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Mother’s milk is complex by nature: so far, more than 200 oligosaccharide structures have been identified in human milk

German et al., 2008



, each of which is expected to have its own potential benefits for infant gut health and immunity. FrieslandCampina Ingredients’ latest GOS innovation, Vivinal® GOS-SL, is a complex solution that contains more than 100 oligosaccharide structures. Some of these structures are present in human milk such as galactosyllactoses 3’-GL, 4’-GL and 6’-GL and sialyllactoses 3’-SL and 6’-SL.

Elevating GOS for infant nutrition

Vivinal® GOS-SL has the same composition as Vivinal® GOS, including 3’-GL, 4’-GL and 6’-GL, but now also contains 3’-SL and 6’-SL from bovine milk origin. 3’-GL, 4’-GL, 6’-GL, 3’-SL and 6’-SL present in Vivinal® GOS-SL have the same structure as the ones in human milk.

*HMO and GOS structures adapted from literature

Thurl et al., 2017
Coulier et al., 2008
Van Leeuwen et al., 2014



Supporting immunity

3’-GL, 4’-GL and 6’-GL have been reported to have anti-inflammatory effects

He et al., 2014



and can promote the growth of beneficial gut bacteria

Li et al., 2015
Meeusen et al., 2024



.

Supporting brain health

3’-SL and 6’-SL have been associated with improved learning & memory, neurodevelopment, language development

Oliveros et al., 2021
Oliveros et al., 2018



and reduced rotavirus, RSV and influenza virus infectivity

Laucirica et al., 2017
Duska-McEwen et al., 2014



.

Supporting gut health

GOS have been shown to stimulate the growth of Bifidobacteria and Lactobacilli

Ben et al., 2008
Fanaro et al., 2009



, support normal gut transit

Williams et al., 2014
Sierra et al., 2014
Costalos et al., 2008
Schmelze et al., 2003



, stool consistency

Sierra et al., 2014



and mineral absorption

Weaver et al., 2011
Whisner et al., 2013
Van den Heuvel et al., 2000
Paganini et al., 2017


Produced through a unique process

Our unique production process ensures SL enrichment and guarantees consistent SL and GL levels in Vivinal® GOS-SL syrup.

  • Process begins by sourcing IFT grade whey permeate containing lactose and SLs.
  • FrieslandCampina Ingredients has developed a selective purification and SL enrichment process to increase SLs on dm to min. 0.45%.
  • Purified lactose stream enriched with SLs is used for enzymatic GOS production resulting in consistent GLs (3’-GL, 4’-GL, 6’-GL) to a level of min. 6.2% on dm.

Powering infant formula with SLs and GLs

Adding 6.5% Vivinal® GOS-SL syrup to an infant formula can provide 25% of the 3’-SL levels and 100% of the GL levels present in mature human milk

Austin et al., 2016
Sumiyoshi et al., 2004



, while supporting key health benefits for infants – gut health, immunity, brain health – and possibly claim 5 HMOs (3’-GL, 4’-GL, 6’-GL, 3’-SL and 6’-SL) on pack and/or on point-of-sales materials*.

*Please note that the country-specific regulation defines what type of communication or claims are allowed per target group and application.

Gut health, immunity and brain health are top concerns of parents of 0-12 months old infants. Globally, 55% of parents find gut health and cognitive development important, while immunity is the #1 concern

Global consumer study Early Life Nutrition Innova and RFC, 2020



.

Want to know more?

As the exclusive provider of GOS enriched with SL structures, we can help you differentiate your infant formula with oligosaccharides. We’re proud to play a global leadership role in the infant milk formula industry, backed by over 75 years of experience in early life nutrition.

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