Immune health of infants and young children matters most to the parents of today, as research from FrieslandCampina Ingredients demonstrates.[1]
It is essential that the newborn’s immune system develops and grows strong in order to reduce the risk of pathogenic infections in early life. As ~70% of the immune system is active in the gut,[2] gut health is strongly linked to immune health.
LNT has been shown to inhibit group B streptococcus[3,4] and Entamoeba histolytica[5] and stimulates the growth of bifidobacterial strains in vitro.[6] By adding LNT to our portfolio, which includes 2’-FL and GOS, we’re perfectly positioned to further explore the benefits of combining oligosaccharides to support gut health and immunity in early life.
Support immune and gut health in early life with Aequival® LNT! Download the datasheet of our newest member of the oligosaccharide portfolio.
References
[1] Global consumer study Early Life Nutrition Innova and RFC, 2020 / selection parents with 0-1 year-old child
[2] Vighi, G., Marcucci, F., Sensi, L., Di Cara, G. & Frati, F. Allergy and the gastrointestinal system. Clin. Exp. Immunol. 153, 3–6 (2008).
[3] Lin, A. E. et al. Human milk oligosaccharides inhibit growth of group B Streptococcus. J. Biol. Chem. 292, 11243–11249 (2017).
[4] Craft, K. M., Thomas, H. C. & Townsend, S. Sialylated variants of Lacto-N-Tetraose exhibit antimicrobial activity against Group B Streptococcus. Org. Biomol. Chem. 17, 1893–1900 (2019).
[5] Jantscher-Krenn, E. et al. Human milk oligosaccharides reduce Entamoeba histolytica attachment and cytotoxicity in vitro. Br. J. Nutr. 108, 1839–1846 (2012).
[6] Asakuma, S. et al. Physiology of consumption of human milk oligosaccharides by infant gut-associated bifidobacteria. J. Biol. Chem. 286, 34583–34592 (2011).